Cancer BiologybioRxiv
An anti-cancer binary system activated by bacteriophage HK022 Integrase
A. Elias, I. Spector, N. Gritsenko…·M. Kolot
This paper develops a new binary cancer gene therapy system using HK022 bacteriophage integrase to specifically activate DTA expression in cancer cells, showing higher efficacy and specificity than a conventional system.
DOI 10.18632/oncotarget.25512