Author

N. Hachmann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:human· 3 Assay:bulk RNA-seq· 1 Organism:non-human primate· 1 Organism:virus· 1

Frequent Co-Authors

J. Miller· 5 shared A.-r. Collier· 4 shared C. Mazurek· 4 shared D. H. Barouch· 4 shared N. Surve· 4 shared O. Powers· 4 shared B. Korber· 3 shared C. Wu· 3 shared

Activity by Year

2022-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersImmunology

J. Miller

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5 papers

Recent·Most cited

Neutralization Escape by SARS-CoV-2 Omicron Subvariant BA.2.86

N. Lasrado, A.-r. Collier, N. Hachmann, J. Miller, M. Rowe, E. Schonberg, S. Rodrigues, A. LaPiana, R. Patio, T. Anand, J. Fisher, C. Mazurek, R. Guan, K. Wagh, J. Theiler, , D. H. Barouch

This study evaluates the neutralization escape of the SARS-CoV-2 Omicron subvariant BA.2.86 compared to other variants, finding lower neutralization by antibodies than BA.2 but comparable to circulating variants.

bioRxiv · Sep 4, 2023Microbiology

Waning Immunity Against XBB.1.5 Following Bivalent mRNA Boosters

N. Lasrado, A.-r. Collier, J. Miller, N. Hachmann, J. Liu, M. Sciacca, C. Wu, T. Anand, E. Bondzie, J. Fisher, C. Mazurek, R. Patio, O. Powers, S. Rodrigues, M. Rowe, , D. H. Barouch

This study evaluates the durability of humoral and cellular immune responses to XBB.1.5 after bivalent mRNA boosters, finding waning neutralizing antibody titers but preserved T cell responses.

bioRxiv · Jan 22, 2023 · PreprintImmunology

Substantial Neutralization Escape by the SARS-CoV-2 Omicron Variant BQ.1.1

J. Miller, N. Hachmann, A.-r. Collier, N. Lasrado, C. Mazurek, R. Patio, O. Powers, N. Surve, J. Theiler, B. Korber, D. H. Barouch

The paper shows BQ.1.1 SARS-CoV-2 variant has greater neutralization escape compared to BA.5, with lower NAb titers in vaccinated individuals.

bioRxiv · Nov 1, 2022 · PreprintImmunology

Immunogenicity of the BA.5 Bivalent mRNA Vaccine Boosters

A.-r. Collier, J. Miller, N. Hachmann, K. McMahan, J. Liu, E. Bondzie, L. Gallup, M. Rowe, E. Shonberg, S. Thai, J. Barrett, E. Borducchi, E. Bouffard, C. Jacob-Dolan, C. Mazurek, , D. Barouch

This study compares neutralizing antibody titers after monovalent and bivalent mRNA boosters against SARS-CoV-2, finding comparable levels against BA.5.

bioRxiv · Oct 24, 2022Immunology

Vaccine Protection Against the SARS-CoV-2 Omicron Variant in Macaques

A. Chandrashekar, J. Yu, K. McMahan, C. Jacob-Dolan, J. Liu, X. He, D. Hope, T. Anioke, J. Barrett, B. Chung, N. Hachmann, M. Lifton, J. Miller, O. Powers, M. Sciacca, , D. H. Barouch

This study evaluates vaccine efficacy against SARS-CoV-2 Omicron in macaques, finding that both humoral and cellular immune responses are necessary for virologic control.

bioRxiv · Feb 6, 2022Microbiology