BiochemistrybioRxiv
Glycosyltransferase POMGNT1 deficiency affects N-cadherin-mediated cell-cell adhesion
S. I. Noor, M. Hoffmann, N. Rinis…·S. Strahl
This study shows that POMGNT1 deficiency increases N-cadherin levels and alters its N-glycan structures, enhancing cell-cell adhesion and activating EMT-like signaling pathways.
DOI 10.1016/j.jbc.2021.100433