Author

N. Klena

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 3 Assay:imaging· 3 Approach:microscopy & imaging analysis· 3 Research Focus:cell signaling & trafficking· 2 Assay:cryo-EM· 2 Organism:human· 2 Organism:mouse· 2

Frequent Co-Authors

G. Pigino· 3 shared B. D. Engel· 2 shared G. Alvarez Viar· 2 shared H. van den Hoek· 2 shared M. Schaffer· 2 shared P. Guichard· 2 shared P. S. Erdmann· 2 shared V. Hamel· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersCell Biology

G. Pigino

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Structure, interaction, and nervous connectivity of beta cell primary cilia

A. Müller, N. Klena, S. Pang, L. E. G. Garcia, O. Topcheva, S. Aurrecoechea Duran, D. Sulaymankhil, M. Seliskar, H. Mziaut, E. Schöniger, D. Friedland, N. Kipke, S. Kretschmar, C. Münster, J. Weitz, , M. Solimena

This study reveals the structural and spatial organization of beta cell primary cilia in mouse and human islets, showing their interactions with neighboring cells and nerves, and their role in islet connectivity.

bioRxiv · Dec 1, 2023Cell Biology

The Tubulin Nano-Code: a protofilament-specific pattern of tubulin post-translational modifications regulates ciliary beating mechanics

G. Alvarez Viar, N. Klena, F. Martino, A. P. Nievergelt, G. Pigino

The paper identifies protofilament-specific tubulin post-translational modification nano-patterns that regulate ciliary beating by interacting with axonemal dyneins and nexin-dynein complexes.

bioRxiv · Jun 28, 2023 · PreprintCell Biology

In situ architecture of the ciliary base reveals the stepwise assembly of IFT trains

H. van den Hoek, N. Klena, M. A. Jordan, G. Alvarez Viar, M. Schaffer, P. S. Erdmann, W. Wan, J. M. Plitzko, W. Baumeister, G. Pigino, V. Hamel, P. Guichard, B. D. Engel

The paper visualizes the native structure of the ciliary transition zone and the stepwise assembly of IFT trains in Chlamydomonas cells.

bioRxiv · Oct 17, 2021 · PreprintCell Biology

Kinesin-1 motility traced by an activity-based precipitating dye

S. Angerani, E. Lindberg, N. Klena, C. K. E. Bleck, C. Aumeier, N. Winssinger

This study develops a fluorogenic substrate that visualizes kinesin-1 motility in live cells by producing a precipitating dye along its transport path.

bioRxiv · Aug 12, 2020 · PreprintBiochemistry

The architecture of the centriole cartwheel-containing region revealed by cryo-electron tomography

N. Klena, M. Le Guennec, A.-M. Tassin, H. van den Hoek, P. S. Erdmann, M. Schaffer, S. Geimer, G. Aeschlimann, L. Kovacik, K. N. Goldie, H. Stahlberg, B. D. Engel, V. Hamel, P. Guichard

This study uses cryo-electron tomography to reveal the architectural diversity of the centriole cartwheel region across four species, showing structural variations in periodicity and organization.

bioRxiv · Jul 21, 2020Cell Biology