BiophysicsbioRxiv
Evolution of an enzyme conformational ensemble guides design of an efficient biocatalyst
A. Broom, R. V. Rakotoharisoa, M. C. Thompson…·R. A. Chica
The paper uses X-ray crystallography to study conformational changes in an evolved enzyme, leading to the design of a more efficient biocatalyst by focusing on active-site mutations.
DOI 10.1038/s41467-020-18619-x