Brain-specific Gata4 downregulation in Greywick female mice models the metabolic subtype of polycystic ovary syndrome
S. A. Nawaito, M. Esmael, O. Souchkova, T. Cardinal, G. Bernas, K.-F. Bergeron, F. Gayda, F. Bergeron, M.-F. Bouchard, X. Zhou, L. Ongaro, D. J. Bernard, J. Short, S. Wray, R. S. Viger, , N. Pilon
This study shows that Gata4 downregulation in the hypothalamus of Greywick female mice models the metabolic subtype of PCOS by affecting fertility and food intake genes.
The FASEB Journal · Jun 30, 2025Peer-reviewedPhysiology