BiophysicsbioRxivPreprint
Distinct neurotoxic TDP-43 fibril polymorphs can be generated by heterotypic interactions with α-synuclein
S. Dhakal, A. S. Robang, N. Bhatt…·V. Rangachari
This study shows that α-synuclein can generate distinct TDP-43 fibril polymorphs through heterotypic interactions, leading to synaptic dysfunction.
DOI 10.1101/2022.06.14.496041