Cancer BiologybioRxiv
Cancer-associated hypersialylated MUC1 drives the differentiation of monocytes into macrophages with a pathogenic phenotype
R. Beatson, R. Graham, F. Grundland Freile…·J. M. Burchell
This study identifies MUC1-ST as a driver of monocyte differentiation into pathogenic macrophages in the tumor microenvironment, associated with poor breast cancer prognosis.
DOI 10.1038/s42003-020-01359-5