A non-ligand surrogate agonist antibody that enhances canonical Wnt signaling and bone regeneration
N.-K. Lee, S. Bidlingmaier, Y. Su, Y. Seo, B. Liu
This paper describes an antibody that enhances Wnt signaling and promotes bone regeneration without requiring exogenous Wnt ligands, showing efficacy in a mouse model of bone loss.
bioRxiv · Sep 25, 2022 · PreprintBioengineering