BiochemistryBiochemistryPeer-reviewed
Melanoma-derived DNA polymerase theta variants exhibit altered DNA polymerase activity
Corey Thomas, Lisbeth Avalos-Irving, Jorge Victorino…·Jamie B. Towle-Weicksel
The paper identifies POLQ gene mutations in melanoma tumors and shows they reduce DNA polymerase activity and accuracy, potentially contributing to cancer progression.
11 citations