BiochemistrybioRxivPreprint
POLQ variants with aberrant DNA polymerase activity protect against UV-induced cell death.
Steven E. Weicksel, Corey Thomas, Ethan Hall…·Jamie B. Towle-Weicksel
This study examines POLQ variants in melanoma tumors, showing they have reduced DNA repair efficiency but can protect against UV-induced cell death.
DOI 10.1101/2025.11.26.690880