Jamie B. Towle-Weicksel

This study examines POLQ variants in melanoma tumors, showing they have reduced DNA repair efficiency but can protect against UV-induced cell death.

This study compares the structure and function of zebrafish and human Pol-Theta, showing conserved features and differences in key loop regions affecting DNA repair mechanisms.

The paper identifies POLQ gene mutations in melanoma tumors and shows they reduce DNA polymerase activity and accuracy, potentially contributing to cancer progression.