Cell BiologyNucleic Acids ResearchPeer-reviewed
Polyubiquitinated PCNA promotes alternative lengthening of telomeres by inducing break-induced replication
Sang‐In Kim, Su Hyung Park, Nalae Kang…·Kyoo‐young Lee
The paper shows polyubiquitinated PCNA promotes break-induced replication at telomeres and fragile sites by recruiting SLX4, leading to telomere damage and DNA synthesis.
15 citations