Interplay between canonical Wnt signaling and α5β1 integrins modulates mechanoresponse in human articular cartilage
Nuria Viudes-Sarrión, Rocío Castro-Viñuelas, Nele Vaes…·Ilse Jonkers
This study investigates how Wnt signaling and α5β1 integrins interact to modulate mechanical responses in human cartilage, showing integrins mediate Wnt-driven changes in load responsiveness.