NeurosciencebioRxivPreprint
Th17 effector cytokines induce shared and distinct microglial and endothelial cell responses in post-streptococcal encephalitis
Charlotte R. Wayne, Uğur Akcan, Travis E. Faust…·Dritan Agalliu
This study identifies IL-17A-IL-17RA signaling in microglia as a critical driver of BBB dysfunction after GAS infections using single-cell RNA sequencing and spatial transcriptomics.