Author
University Medical Center Groningen
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
6 papers
Recent·Most cited
Daniëlle C. Voshart, Takuya Oshima, Yuting Jiang…·Lara Barazzuol
This study shows that radiotherapy primes microglia in rats to have a heightened immune response to future inflammation, and this effect is observed in human brain tissue.
Kitty Reemst, Laura Kracht, Janssen M. Kotah…·Anikó Kőrösi
This study shows that early-life stress alters microglial transcriptome and function in mice, affecting phagocytic capacity and gene expression in adulthood.
Xiaoming Zhang, Laura Kracht, Antônio Marcondes Lerário…·Susanne M. Kooistra
The paper investigates how epigenetic changes in microglia influence their response to inflammatory and genotoxic stress, identifying distinct gene networks and functional phenotypes.
Anneke Miedema, Emma Gerrits, Nieske Brouwer…·Susanne M. Kooistra
The paper identifies early transcriptomic changes in brain macrophages in MS tissue, linking them to lesion development and suggesting potential therapeutic targets.
Astrid M. Alsema, Qiong Jiang, Laura Kracht…·Bart J. L. Eggen
The paper profiles microglia transcriptomes in AD donors and non-demented elderly using bulk and single-cell RNA sequencing, finding no significant differences in gene expression or subcluster composition.
Thecla A. van Wageningen, Emma Gerrits, A. Geleijnse…·A.-M. van Dam
The paper compares gene expression profiles of demyelinated white and grey matter in MS patients, finding minimal overlap and distinct glial cell signatures.