Author

Nikola Holodkov

International Centre for Genetic Engineering and Biotechnology

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Neuroscience· 1

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Organism:Drosophila· 1 Approach:experimental assay· 1

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Fabian M. FeiguiniD· 1 shared Giulia RomanoiD· 1 shared Raffaella KlimaiD· 1 shared

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2021-2021 · peak 1/yr

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1 shared paperNeuroscience

Fabian M. FeiguinORCID

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NeuroscienceScientific ReportsPeer-reviewedSep 21, 2021

TDP-43 regulates GAD1 mRNA splicing and GABA signaling in Drosophila brains

Giulia Romano, Nikola Holodkov, Raffaella Klima, Fabian M. Feiguin

This study shows that TDP-43 regulates GAD1 mRNA splicing and GABA signaling in Drosophila brains, and that modulating GABA neurotransmission can reverse locomotion defects in TDP-43-deficient flies.

15 citations

Drosophilaexperimental assay

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