NeuroscienceNeurobiology of DiseasePeer-reviewed
Diet-induced metabolic and immune impairments are sex-specifically modulated by soluble TNF signaling in the 5xFAD mouse model of Alzheimers disease
Maria Elizabeth de Sousa Rodrigues, MacKenzie L. Bolen, Lisa Blackmer‐Raynolds…·Timothy Robert Sampson
The paper shows that a high-fat, high-carbohydrate diet causes sex-specific metabolic and inflammatory issues in 5xFAD mice, which are partially reversed by inhibiting soluble TNF in males.
9 citations