Phage DNA polymerase prevents deleterious on-target damage and enhances precise CRISPR/Cas9 editing
Q. Yang, J. S. Abebe, M. Mai, G. Rudy, S. Y. Kim, O. Devinsky, C. Long
This study identifies T4 DNA polymerase as a tool to enhance CRISPR/Cas9 editing precision by reducing on-target deletions and translocations while increasing insertion accuracy.
bioRxiv · Jan 10, 2023 · PreprintBioengineering