Sulfite oxidase deficiency causes persulfidation loss and H2S release
C.-Y. Fu, J. B. Kohl, F. Liebsch, D. D`Andrea, M. Mai, A. T. Mellis, E. Kouroussis, T. Ditroi, J. A. Santamaria-Araujo, S. Y. Yeo, H. Endepols, M. Krizkov, V. Kozich, U. Barayeu, T. Akaike, , G. Schwarz
This study shows that SOX deficiency leads to persulfidation loss and increased H2S release, with thiosulfate accumulation and metabolic rewiring in a mouse model.
bioRxiv · Mar 13, 2024 · PreprintBiochemistry