O. Koren

Aggression: A gut reaction? The effects of gut microbiome on aggression

The study investigates how gut microbiome alterations affect aggression in mice, finding that reduced microbiota increases aggression, which can be reversed by restoring a wild-type microbiota.

An experimental approach towards untangling the role of nature versus nurture in shaping the microbiome of social insects

The paper investigates how host identity and environment shape microbiomes in social insects, finding environment drives adult microbiomes while host species differences affect larvae.

Acetylation-dependent coupling between G6PD activity and apoptotic signaling

This study shows acetylation of G6PD regulates its activity and links to apoptotic signaling through structural and functional analyses.

Metabolic rewiring of the probiotic bacterium Lacticaseibacillus rhamnosus GG contributes to cell wall remodeling and antimicrobials production

This study shows that fermentation in LGG alters its metabolome, proteome, and cell wall properties, enhancing antimicrobial activity against pathogens.

Context-dependent differences in the functional responses of Lactobacillaceae strains to fermentable sugars

The paper compares how five Lactobacillaceae strains respond to fermentable sugars in free-living and biofilm states, finding strain-specific differences in carrying capacity and acid tolerance.

Tryptophol acetate and tyrosol acetate, small molecule metabolites identified in a probiotic mixture, inhibit hyperinflammation

This study identifies two small molecule metabolites from a probiotic yeast that inhibit hyperinflammation by modulating immune signaling pathways.

Progesterone supplementation in mice leads to microbiome alterations and weight gain in a sex-specific manner

This study shows progesterone increases weight in female mice but not males, with microbiome changes in females only, suggesting sex-specific microbiota involvement in progesterone effects.

MIPMLP - Microbiome Pre-processing Machine Learning Pipeline.

The paper develops a preprocessing pipeline for 16S sequencing data to improve machine learning classification accuracy by optimizing feature representation and dimensionality reduction.

Antibiotics increase aggression behavior and aggression-related pheromones and receptors in Drosophila melanogaster

This study shows that antibiotics increase aggression in Drosophila by elevating aggression-related pheromones and their receptors.

Projection of gut microbiome pre and post-bariatric surgery to predict surgery outcome

The paper projects gut microbiome data pre and post-bariatric surgery to predict BMI loss, identifying distinct microbiome profiles associated with different outcomes.

Interactions between the gut microbiome and mucosal immunoglobulins A, M and G in the developing infant gut

The paper examines how IgA, IgM, and IgG interact with the gut microbiome in infants, finding that IgA and IgM coat similar microbes while IgG targets different ones, and breastfeeding influences these interactions.