A. Cohen

Engineering of methionine-auxotroph Escherichia coli via parallel evolution of two enzymes from Corynebacterium glutamicum's direct-sulfurylation pathway enables its recovery in minimal medium

This paper engineers methionine-auxotroph E. coli by evolving enzymes from C. glutamicum to enable growth in minimal medium.

Anti-fungal recombinant psoriasin effectively inhibits Candida albicans growth on denture base

This study evaluates psoriasin's ability to inhibit Candida albicans growth on denture bases, finding it effectively eradicates fungal growth when applied to the material.

An experimental approach towards untangling the role of nature versus nurture in shaping the microbiome of social insects

The paper investigates how host identity and environment shape microbiomes in social insects, finding environment drives adult microbiomes while host species differences affect larvae.

Microcalcifications can either trigger or suppress breast precancer malignancy potential according to the mineral type in a 3D tumor model

This study shows that different types of microcalcifications affect breast precancer progression differently in a 3D tumor model, with apatite promoting malignancy and calcium oxalate dihydrate suppressing it.

ABA-IMPORTING TRANSPORTER 1.1 activity in the endosperm of tomato seeds restrains germination under salinity stress

This study shows that AIT1.1 in tomato endosperm mediates ABA uptake to restrain germination under salinity stress, with ait1.1 mutants showing improved germination.

Genome-scale CRISPR screening reveals that C3aR signaling is critical for rapid capture of fungi by macrophages

This study uses CRISPR screening to identify C3aR as critical for macrophage capture of fungi, revealing a novel role in fungal pathogen recognition.

Cooperative Allostery and Structural Dynamics of Streptavidin at Cryogenic- and Ambient-temperature

The paper presents two apo-streptavidin structures at different temperatures and reveals cooperative allostery through water-mediated interactions.

Guanine content of microRNAs is associated with their tumor suppressive and oncogenic roles in lung and breast cancers

The paper links guanine content in miRNA precursor terminal loops and mature forms to their tumor suppressive or oncogenic roles in lung and breast cancers.

Large-scale quantification of human osteocyte lacunar morphological biomarkers as assessed by ultra-high-resolution desktop micro-computed tomography

This study assesses the accuracy, reproducibility, and sensitivity of ultra-high-resolution desktop micro-CT for large-scale quantification of human osteocyte lacunar morphometry in clinical biopsies.

Lipidome profiles of plasma microvesicles differ in experimental cerebral malaria, compared to malaria without neurological complications

The paper compares lipidome profiles of plasma microvesicles in experimental cerebral malaria and non-CM malaria, finding distinct lipid changes associated with CM.

Multimodal magnetic resonance imaging predicts regional amyloid-β burden in the brain

This study uses MRI modalities and machine learning to predict amyloid-β burden in the brain, showing that combined T1, T2, and SWI images perform best.