Systems BiologyPLoS Computational BiologyPeer-reviewed
A rule-based multiscale model of hepatic stellate cell plasticity: critical role of the inactivation loop in fibrosis progression
Matthieu Bouguéon, Vincent Legagneux, Octave Hazard…·Nathalie Théret
This paper develops a rule-based model of hepatic stellate cell dynamics in fibrosis, showing the critical role of inactivation loops in fibrosis progression and identifying inactivated HSCs as markers of fibrosis.
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