BiochemistryJournal of Medicinal ChemistryPeer-reviewed
Rational Design and Optimization of a Potent IDO1 Proteolysis Targeting Chimera (PROTAC)
Paige J. Monsen, Prashant V. Bommi, Arabela A. Grigorescu…·Gary E. Schiltz
This study optimizes a PROTAC to degrade IDO1 with high potency in GBM cells, showing sustained degradation via the ubiquitin-proteasome system.
27 citationstop 1%