Author

Omar Ashraf Harb

University of Virginia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Molecular Biology· 1

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Approach:experimental assay· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1

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Ariadna RobledoiD· 1 shared Carlos Perfecto Flores Suarez· 1 shared Emily K. Alley· 1 shared Gabrielle E. LargozaiD· 1 shared Ionela IacobasiD· 1 shared Jason E. FishiD· 1 shared John J. Ahn· 1 shared Joshua D. WytheiD· 1 shared

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Ariadna RobledoORCID

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1 paper

Recent·Most cited

Molecular BiologybioRxivPreprintMay 15, 2024

MEK signaling represents a viable therapeutic vulnerability of KRAS-driven somatic brain arteriovenous malformations

Carlos Perfecto Flores Suarez, Omar Ashraf Harb, Ariadna Robledo…·Joshua D. Wythe

This study shows that KRAS mutations drive brain arteriovenous malformations (bAVMs) in specific brain regions and that MEK inhibition can reduce their severity in mice, suggesting a potential therapeutic approach for human bAVMs.

5 citations

mousehuman

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