Author

Owen P. Smith

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Amélie Trinquand· 1 shared Colm J. RyaniD· 1 shared Cosmin TudoseiD· 1 shared Giorgio Oliviero· 1 shared Jonathan BondiD· 1 shared Kieran Wynne· 1 shared Luke JonesiD· 1 shared Marc R. Mansour· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Amélie Trinquand

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintAug 4, 2023

Loss of Polycomb Repressive Complex 2 function causes asparaginase resistance in T-acute lymphoblastic leukemia through decreased WNT pathway activity

Thomas Lefeivre, Cosmin Tudose, Theodora-Ioana Grosu…·Jonathan Bond

The paper identifies that PRC2 loss in T-ALL reduces WNT pathway activity, leading to asparaginase resistance, which can be overcome by proteasome inhibition.

DOI 10.1101/2023.08.04.552014

humanproteomics

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