D. Samanta

Coxiella burnetii-containing vacuoles interact with host recycling-endosomal proteins Rab11a and Rab35 for vacuolar expansion

This study shows Coxiella burnetii-containing vacuoles interact with host Rab11a and Rab35 for vacuolar expansion, with Rab11a and Rab35 expression patterns changing over infection stages.

In silico and in vitro characterization of the mycobacterial protein Ku to unravel its role in non-homologous end-joining DNA repair

The paper characterizes the DNA binding properties of mycobacterial Ku (mKu) and its role in NHEJ using in silico and in vitro methods, showing its ability to stabilize DNA and protect termini from degradation.

Next Generation Nanopore Sensors for Enhanced Detection of Nanoparticles

This paper develops enhanced nanopore sensors with a polymer electrolyte system to analyze heterogeneous nanoparticle mixtures at low ionic strength, demonstrating their applicability to various nanoparticle types.

Enrichment of breast cancer stem cells following cytotoxic chemotherapy is mediated by hypoxia-inducible factors

This study shows that cytotoxic chemotherapy in TNBC increases BCSCs via HIFs, leading to relapse, and that HIF inhibitors can block this effect.

Architecture of the linker-scaffold in the nuclear pore

The paper establishes the near-atomic molecular architecture and evolutionary conservation of the linker-scaffold in the human nuclear pore complex.

Coxiella burnetii Type 4B Secretion System-dependent manipulation of endolysosomal maturation is required for bacterial growth

This study shows that Coxiella burnetii uses its Type 4B Secretion System to block endosomal acidification, preventing lysosome fusion and maintaining a less acidic vacuole that supports bacterial growth.