P. Breen

Perturbed sulfur homeostasis allows C. elegans to escape growth retardation on Actinobacteria from its natural microbiome

This study identifies mutations in sulfur metabolism genes that allow C. elegans to escape growth retardation on Actinobacteria from its natural microbiome.

The Klebsiella pneumoniae citrate synthase gene, gltA, influences site specific fitness during infection

This study identifies the Kp citrate synthase gene gltA as critical for metabolic flexibility during infection, showing organ-specific fitness defects in lung and gut colonization.