G. Ruvkun

Mitochondrial fission surveillance is coupled to Caenorhabditis elegans DNA and chromosome segregation integrity

The paper identifies genes regulating mitochondrial fission in C. elegans and shows that chromosome missegregation leads to mitochondrial fission dysregulation, independent of Drp-1.

Perturbed sulfur homeostasis allows C. elegans to escape growth retardation on Actinobacteria from its natural microbiome

This study identifies mutations in sulfur metabolism genes that allow C. elegans to escape growth retardation on Actinobacteria from its natural microbiome.

Lysosomal activity regulates Caenorhabditis elegans mitochondrial dynamics through vitamin B12 metabolism

This study shows that lysosomal activity in C. elegans regulates mitochondrial fission through vitamin B12 metabolism, linking lysosomal dysfunction to mitochondrial dynamics and micronutrient deficiency.