P. Buckley

Sequence independent activity of a predicted long disordered segment of the human papillomavirus L2 capsid protein during virus entry

The paper shows that the length, not the sequence, of a disordered segment in HPV16 L2 protein determines its activity during virus entry.

HLA-dependent variation in SARS-CoV-2 CD8+ T cell cross-reactivity with human coronaviruses

This study identifies SARS-CoV-2 peptides with cross-reactivity to human coronaviruses and shows that TCR repertoires in COVID-19 patients are HLA-dependent.

Evaluating performance of existing computational models in predicting CD8+ T cell pathogenic epitopes and cancer neoantigens

This study evaluates existing computational models for predicting CD8+ T cell epitopes and cancer neoantigens, finding poor performance for emerging viruses and cancer peptides.

TRM Integrins CD103 and CD49a Differentially Support Adherence and Motility After Resolution of Influenza Virus Infection

This study shows CD103 and CD49a on TRM cells have distinct roles in adherence and motility, impacting TRM retention and host protection after influenza infection.

CD8+ T cell cross-reactivity against SARS-CoV-2 conferred by other coronavirus strains and influenza virus

The paper investigates T cell cross-reactivity against SARS-CoV-2 from other coronaviruses and influenza virus, identifies epitopes, and supports vaccine development.