Cancer BiologybioRxiv
MTHFD1 is a genetic interactor of BRD4 and links folate metabolism to transcriptional regulation
S. Sdelci, A. Rendeiro, P. Rathert…·S. Kubicek
This study identifies MTHFD1 as a genetic and physical interactor of BRD4, linking folate metabolism to transcriptional regulation and showing synergistic effects on cancer cell viability.