Author

P. Cahan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. Tam· 1 shared C. Cherry· 1 shared C. Plaisier· 1 shared D. Cats· 1 shared D. M. Pardoll· 1 shared D. Pearson· 1 shared D. R. Maestas· 1 shared E. L. da Rocha· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperImmunology

A. Tam

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Synthetic Maturation of Multilineage Human Liver Organoids via Genetically Guided Engineering

J. J. Velazquez, R. LeGraw, F. Moghadam, Y. Tan, J. Kilbourne, J. Hislop, S. Liu, D. Cats, S. M. Chuva de Sousa Lopes, C. Plaisier, P. Cahan, S. Kiani, M. R. Ebrahimkhani

This paper demonstrates genetic engineering of liver organoids to enhance maturation and functionality through CRISPR and transcription factor overexpression.

bioRxiv · May 10, 2020Bioengineering

Single cell RNA-seq in regenerative and fibrotic biomaterial environments defines new macrophage subsets

S. D. Sommerfeld, C. Cherry, R. M. Schwab, L. Chung, D. R. Maestas, P. Laffont, J. E. Stein, A. Tam, F. Housseau, J. M. Taube, D. M. Pardoll, P. Cahan, J. H. Elisseeff

The paper uses single-cell RNA sequencing to identify distinct macrophage subsets in regenerative and fibrotic environments, revealing new phenotypes and potential therapeutic targets.

bioRxiv · May 20, 2019Immunology

Short hairpin RNAs artifactually impair cell growth and suppress clustered microRNA expression.

J. Powers, E. L. da Rocha, D. Pearson, P. Missios, T. Y. de Soysa, J. Barragan, P. Cahan, G. Daley

This study shows that shRNAs impair cell growth and suppress microRNA expression in a sequence-independent manner, highlighting potential artifacts in cancer research.

bioRxiv · Dec 11, 2018 · PreprintCancer Biology