MITF reprograms the extracellular matrix and focal adhesion in melanoma
R. Dilshat, V. Fock, C. Kenny, I. Gerritsen, R. M. J. Lasseur, O. Eichhoff, J. Travnickova, P. Cerny, K. Moller, S. Sigurbjornsdottir, K. Kirty, B. O. Einarsdottir, P. F. Cheng, M. Levesque, R. Cornell, , E. Steingrimsson
This study shows MITF represses ECM and focal adhesion genes in melanoma, affecting cell morphology and matrix interactions, with reversible effects observed upon MITF knockdown.
bioRxiv · Jul 14, 2020Cancer Biology