Author

E. E. Patton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Approach:experimental assay· 5 Organism:zebrafish· 5 Research Focus:drug response / drug discovery· 2 Assay:imaging· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

J. Travnickova· 3 shared A. Brombin· 2 shared Y. Lu· 2 shared A. Coates· 1 shared A. H. Y. Chan· 1 shared A. I. Young· 1 shared A. V. Kriegsheim· 1 shared B. O. Einarsdottir· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCancer Biology

J. Travnickova

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

ALDH1A3-acetaldehyde metabolism potentiates transcriptionalheterogeneity in melanoma

Y. Lu, J. Travnickova, M. Badonyi, F. Rambow, A. Coates, Z. Khan, J. Marques, L. Murphy, P. Garcia-Martinez, R. Marais, P. Louphrasitthiphol, A. H. Y. Chan, C. J. Schofield, A. V. Kriegsheim, J. A. Marsh, , E. E. Patton

This study shows ALDH1A3 and ACSS2 coordinate acetaldehyde-acetyl-CoA metabolism with histone acetylation in melanoma, contributing to transcriptional heterogeneity and drug resistance.

bioRxiv · Oct 28, 2023Cancer Biology

Fate mapping melanoma persister cells through regression and into recurrent disease in adult zebrafish

J. Travnickova, S. Muise, S. Wojciechowska, A. Brombin, Z. Zeng, A. I. Young, C. Wyatt, E. E. Patton

The paper tracks melanoma persister cells in zebrafish to show their role in recurrent disease.

bioRxiv · Mar 17, 2022Cancer Biology

Long-term non-invasive drug treatments for adult zebrafish

Y. Lu, E. E. Patton

This paper develops a non-invasive drug administration method for adult zebrafish using food-based drug pellets, enabling long-term treatment studies and modeling drug resistance in melanoma.

bioRxiv · Dec 21, 2021 · PreprintCancer Biology

Aldh2 is a lineage-specific metabolic gatekeeper in melanocyte stem cells

H. Brunsdon, A. Brombin, S. Peterson, J. H. Postlethwait, E. E. Patton

The paper identifies Aldh2 as a metabolic gatekeeper in zebrafish melanocyte stem cells during regeneration, showing it enables formate production for nucleotide biosynthesis.

bioRxiv · Sep 23, 2021Cell Biology

MITF reprograms the extracellular matrix and focal adhesion in melanoma

R. Dilshat, V. Fock, C. Kenny, I. Gerritsen, R. M. J. Lasseur, O. Eichhoff, J. Travnickova, P. Cerny, K. Moller, S. Sigurbjornsdottir, K. Kirty, B. O. Einarsdottir, P. F. Cheng, M. Levesque, R. Cornell, , E. Steingrimsson

This study shows MITF represses ECM and focal adhesion genes in melanoma, affecting cell morphology and matrix interactions, with reversible effects observed upon MITF knockdown.

bioRxiv · Jul 14, 2020Cancer Biology