Author

V. Fock

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

A. Bykov· 1 shared B. O. Einarsdottir· 1 shared B. Radic Sarikas· 1 shared B. Sax· 1 shared C. Kenny· 1 shared E. E. Patton· 1 shared E. Magnusdottir· 1 shared E. Steingrimsson· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

A. Bykov

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

YAP1 is a key regulator of EWS::FLI1-dependent malignant transformation upon IGF-1 mediated reprogramming of bone mesenchymal stem cells

H. Kovar, R. Noorizadeh, B. Sax, T. Javaheri, B. Radic Sarikas, V. Fock, M. Kauer, A. Bykov, V. Suresh, M. Schlederer, L. Kenner, G. Weber, W. Mikulits, F. Halbritter, R. Moriggl

The paper shows that IGF-1 reprograms bone mesenchymal stem cells in EWS::FLI1-mutant mice, leading to tumor formation, with Yap1 playing a central role, and suggests combined IGF-1R and YAP/TEAD inhibition as a potential treatment.

bioRxiv · Jul 15, 2024Cancer Biology

MITF reprograms the extracellular matrix and focal adhesion in melanoma

R. Dilshat, V. Fock, C. Kenny, I. Gerritsen, R. M. J. Lasseur, O. Eichhoff, J. Travnickova, P. Cerny, K. Moller, S. Sigurbjornsdottir, K. Kirty, B. O. Einarsdottir, P. F. Cheng, M. Levesque, R. Cornell, , E. Steingrimsson

This study shows MITF represses ECM and focal adhesion genes in melanoma, affecting cell morphology and matrix interactions, with reversible effects observed upon MITF knockdown.

bioRxiv · Jul 14, 2020Cancer Biology