P. Cruz-Morales

This study uses RB-TnSeq to functionally analyze fatty acid and alcohol metabolism in Pseudomonas putida, identifying gene roles and catabolic pathways for isoprenol and isopentanol.

The paper introduces ActDES, a curated database of 612 high-quality actinobacterial genomes, to facilitate evolutionary and metabolic studies.

This study uses chemoinformatics to engineer polyketide synthases for producing saturated β-carbon compounds, finding a correlation between chemical similarity and product titers.

This study characterizes the ECF56-family sigma factor from Streptomyces venezuelae, showing its C-terminal extension is conserved and regulates a highly conserved regulome across Actinobacteria.

This paper investigates the structural mechanism of regioselectivity in a bacterial acyl-CoA dehydrogenase, identifying key residues and structural features responsible for its unique substrate specificity.

This paper uses RB-TnSeq to identify novel enzymes in Pseudomonas putida lysine metabolism, revealing new biochemical pathways and functions for DUF1338 proteins.

This study uses genomic data from 779 strains to revise the taxonomy of Clostridia, revealing multiple genera and inconsistencies in current classification.

The paper shows that gene family expansions in central carbon metabolism in Streptomyces bacteria contribute to metabolic robustness needed for antibiotic biosynthesis.