A. Pearson

Environmental controls on crenarchaeol distributions in hydrothermal springs

The paper quantifies iGDGT composition in thermal springs to investigate how pH and temperature influence crenarchaeol abundance and membrane lipid structure in archaea.

Crystal structure of a bacterial photoactivated adenylate cyclase determined at room temperature by serial femtosecond crystallography

The paper determines the crystal structure of a bacterial photoactivated adenylate cyclase at room temperature using serial femtosecond crystallography and compares it with cryo structures to study structural changes upon light exposure.

Metabolic imprints in the hydrogen isotopes of Archaeoglobus fulgidus tetraether lipids

This study investigates how metabolism and growth conditions affect hydrogen isotope signatures in archaeal lipids, supporting their use as paleohydrological proxies.

Mode of carbon and energy metabolism shifts lipid composition in the thermoacidophile Acidianus

This study shows that changes in energy and carbon metabolism in Acidianus sp. DS80 significantly affect the ring index of its membrane lipids, indicating a link between cellular energy state and lipid composition.

Distribution of carbon monoxide (CO) in several tissues from Atlantic bottlenose dolphins (Tursiops truncatus)

This study measures carbon monoxide concentrations in nine tissues of stranded Atlantic bottlenose dolphins, finding higher levels in liver, skeletal muscle, and spleen, and lower levels in infected animals.

Functional and structural asymmetry suggest a unifying principle for catalysis in integral membrane-bound pyrophosphatases

This study presents the first structure of a K+-independent M-PPase and shows asymmetric and time-dependent substrate binding, proposing a unified model for ion pumping and energy coupling in M-PPases.

Elevated genetic risk for multiple sclerosis originated in Steppe Pastoralist populations

This study identifies the origin of genetic risk variants for multiple sclerosis in Steppe pastoralist populations and traces their spread into Europe through migration.

The Selection Landscape and Genetic Legacy of Ancient Eurasians

This study models ancient Eurasian selection landscapes and shows ancestry-specific genetic risk associations with modern phenotypes.

Population Genomics of Postglacial Western Eurasia

This study analyzes ancient genomes from Western Eurasia to trace postglacial human migrations and genetic changes across the Holocene.

Functional analysis of the fatty acid and alcohol metabolism of Pseudomonas putida using RB-TnSeq

This study uses RB-TnSeq to functionally analyze fatty acid and alcohol metabolism in Pseudomonas putida, identifying gene roles and catabolic pathways for isoprenol and isopentanol.

Generated randomly and selected functionally? The nature of enterovirus recombination

This study investigates the factors influencing recombination in poliovirus, finding that genome function and fitness, rather than sequence identity or structure, determine the identity of recombinant progeny.

Multiple environmental parameters impact core lipid cyclization in Sulfolobus acidocaldarius

This study investigates how environmental factors affect lipid cyclization in Sulfolobus acidocaldarius, finding that growth rate correlates with cyclization and suggesting energy availability as a universal driver.

Energy flux controls tetraether lipid cyclization in Sulfolobus acidocaldarius

This paper shows that energy flux affects GDGT cyclization in archaea, linking membrane composition to energy availability across different growth conditions.

Illuminating microbial species-specific effects on organic matter remineralization in marine sediments

The paper investigates how microbial species-specific metabolic capabilities affect organic matter remineralization in marine sediments, showing species-specific differences in carbon utilization rates and types.