Evolutionary BiologybioRxiv
An early cell shape transition drives evolutionary expansion of the human forebrain
S. Benito-Kwiecinski, S. L. Giandomenico, M. Sutcliffe…·M. A. Lancaster
The paper uses cerebral organoids to show that a delayed cell shape transition in human neuroepithelial cells drives brain expansion compared to apes.
DOI 10.1016/j.cell.2021.02.050