Cell BiologybioRxiv
Flexible fitting of PROTAC concentration-response curves with changepoint Gaussian Processes
E. Semenova, M. L. Guerriero, B. Zhang…·S. E. Lazic
This paper introduces a Bayesian changepoint Gaussian Processes model to automatically fit PROTAC concentration-response curves, enabling accurate parameter estimation and compound ranking without manual intervention.
DOI 10.1177/24725552211028142