Solid Phase Synthesis of Fluorosulfate Containing Macrocycles for Chemoproteomic Workflows
F. F. Faucher, D. Abegg, P. Ipock, A. Adibekian, S. Lovell, M. Bogyo
The paper describes a solid-phase synthesis method for creating macrocyclic peptides with fluorosulfate electrophiles, enabling chemoproteomic screening and target identification.
bioRxiv · Feb 17, 2023Biochemistry