Author

F. F. Faucher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:plant (other)· 2 Assay:proteomics· 2

Frequent Co-Authors

M. Bogyo· 3 shared A. Adibekian· 2 shared D. A. Fidock· 2 shared D. Abegg· 2 shared E. Yeh· 2 shared J. M. Bennett· 2 shared S. Kabeche· 2 shared S. Lovell· 2 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersMicrobiology

M. Bogyo

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mixed Alkyl/Aryl Phosphonates Identify Metabolic Serine Hydrolases as Antimalarial Targets

J. M. Bennett, S. K. Narwal, S. Kabeche, D. Abegg, F. Hackett, T. Yeo, V. Li, R. K. Muir, F. F. Faucher, S. Lovell, M. Blackman, A. Adibekian, E. Yeh, D. A. Fidock, M. Bogyo

The paper identifies mixed alkyl/aryl phosphonates as anti-malarial compounds that inhibit serine hydrolases with low resistance potential.

Cell Chemical Biology · Sep 1, 2024Peer-reviewedMicrobiology

Covalent macrocyclic proteasome inhibitors mitigate resistance in Plasmodium falciparum

J. M. Bennett, K. E. Ward, R. Muir, S. Kabeche, E. Yoo, T. Yeo, G. Lam, H. Zhang, J. Almaliti, G. Berger, F. F. Faucher, G. Lin, W. H. Gerwick, E. Yeh, D. A. Fidock, M. Bogyo

This paper develops covalent macrocyclic proteasome inhibitors for Plasmodium falciparum that show reduced resistance compared to reversible inhibitors.

bioRxiv · Jul 3, 2023 · PreprintMicrobiology

Solid Phase Synthesis of Fluorosulfate Containing Macrocycles for Chemoproteomic Workflows

F. F. Faucher, D. Abegg, P. Ipock, A. Adibekian, S. Lovell, M. Bogyo

The paper describes a solid-phase synthesis method for creating macrocyclic peptides with fluorosulfate electrophiles, enabling chemoproteomic screening and target identification.

bioRxiv · Feb 17, 2023Biochemistry