Cancer BiologybioRxivPreprint
Direct therapeutic targeting of SWI/SNF induces epigenetic reprogramming and durable tumor regression in rhabdoid tumor
M. H. Chasse, B. K. Johnson, E. A. Boguslawski…·P. J. Grohar
This paper shows that targeting the SWI/SNF complex with mithramycin and its analogue EC8042 induces epigenetic reprogramming and durable tumor regression in rhabdoid tumors.