P. J. Saez

This study shows that lateral confinement controls pericyte shape and migration, with dry friction theory accurately predicting their behavior in vitro.

The paper presents a theoretical model predicting oscillations in cellular polarization during directional decision-making at junctions, validated experimentally in two cell types.

This paper identifies septins as key regulators of amoeboid motility in T cells by enabling microenvironment sensing and actomyosin partitioning through steric interactions with collagen fibers.

The paper measures cortical thickness in live cells using magnetic beads and finds it is dynamic and fluctuates due to actomyosin contractility.

This study shows that mechanical forces at the immune synapse are spatially and temporally patterned by actomyosin dynamics, with global contractile forces at the periphery and local forces at the center, which regulate endocytosis.