Cell BiologybioRxivPreprint
Loss of PKCα increases arterial medial calcification in a uremic mouse model of chronic kidney disease
S. J. Borland, C. Facchi, J. Behnsen…·A. E. Canfield
This study shows that PKC loss increases uremia-induced arterial medial calcification in mice, suggesting PKC/TGF-β signaling as a therapeutic target.