Author

P. K. Javaregowda

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. UMEZAWA· 3 shared A. Nakazawa· 2 shared H. Nonaka· 2 shared K. Ite· 2 shared M. Kasahara· 2 shared M. Toyoda· 2 shared N. Saku· 2 shared S. Miyata· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCell Biology

A. UMEZAWA

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Author profile →

3 papers

Recent·Most cited

Cell BiologybioRxivMar 3, 2023

Functional and long-lived melanocytes from human pluripotent stem cells with transient ectopic expression of JMJD3

C. Kobori, R. Takagi, R. Yokomizo…·A. UMEZAWA

This study generates functional and long-lived melanocytes from human pluripotent stem cells using transient JMJD3 expression, showing melanogenesis and engraftability in mice.

DOI 10.1186/s13287-023-03479-1

humanbulk RNA-seq

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Cell BiologybioRxivPreprintApr 25, 2020

Puromycin selection of cells with a high expression of the cytochrome P450 CYP3A4 gene activity from a patient with drug-induced liver injury (DILI) and their lifespan prolongation using a combination of CDK4R24C, cyclin D1 and TERT

S. Miyata, N. Saku, P. K. Javaregowda…·A. Umezawa

The paper generates an immortalized hepatocyte cell line with high CYP3A4 expression from a DILI patient and shows its prolonged lifespan and drug-metabolism capacity.

DOI 10.1101/2020.04.25.061275

humanbulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivMar 20, 2020

Ammonia-based enrichment and long-term propagation of zone I hepatocyte-like cells

R. Tsuneishi, N. Saku, S. Miyata…·A. Umezawa

This study shows that ammonia treatment enriches hepatocyte-like cells derived from human pluripotent stem cells, which can be propagated long-term in vitro while maintaining liver-specific gene expression.

DOI 10.1038/s41598-021-90708-3

humanscRNA-seq

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