MicrobiologybioRxiv
Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183
L. E. de Vries, P. A. Jansen, C. Barcelo…·K. J. Dechering
This paper characterizes MMV693183, a novel antimalarial compound targeting acetyl-CoA synthetase, showing in vitro and in vivo efficacy against Plasmodium species and transmission blocking.