Author

P. Lafaye

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

A. Arbabian· 1 shared A. Bertin· 1 shared A. Charles-Orszag· 1 shared A. Haouz· 1 shared A. Mallet· 1 shared A. Salles· 1 shared A. Vanderplasschen· 1 shared C. Blanc· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperBiochemistry

A. Arbabian

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structural basis of TMPRSS2 zymogen activation and recognition by the HKU1 seasonal coronavirus

I. Fernandez, N. Saunders, S. Duquerroy, W. H. Bolland, A. Arbabian, E. Baquero, C. Blanc, P. Lafaye, A. Haouz, J. Buchrieser, O. Schwartz, F. A. Rey

This study determines the structure of HKU1-CoV receptor binding domain in complex with TMPRSS2, identifying key residues for host tropism and revealing the structural basis of TMPRSS2 activation.

bioRxiv · Feb 21, 2024Biochemistry

Development of nanobodies as theranostic agents against CMY-2-like class C β-lactamases

F. Cawez, P. S. Mercuri, F. M. Yanez, R. Maalouf, M. Vandevenne, F. Kerff, V. Guerin, J. G. Mainil, D. Thiry, M. Salmon, A. Vanderplasschen, P. Lafaye, G. Ayme, P. Bogaerts, M. Dumoulin, M. Galleni

This study identifies VHH nanobodies that inhibit CMY-2 class C β-lactamases and develops an ELISA for detecting these enzymes in resistant bacteria.

bioRxiv · Jul 1, 2022 · PreprintBiochemistry

Adhesion to nanofibers drives cell membrane remodeling through 1D wetting

A. Charles-Orszag, F.-C. Tsai, D. Bonazzi, V. Manriquez, M. Sachse, A. Mallet, A. Salles, K. Melican, R. Staneva, A. Bertin, C. Millien, S. Goussard, P. Lafaye, S. Shorte, M. Piel, , G. Dumenil

This study identifies a novel physical mechanism, 1D wetting, by which Neisseria meningitidis drives plasma membrane remodeling on nanofibers independent of F-actin.

bioRxiv · Aug 16, 2018 · PreprintCell Biology