Systemic influences of mammary cancer on monocytes in mice
A. Robinson, M. Burgess, S. Webb, P. Louwe, Z. Ouyang, D. Skola, C. Z. Han, N. N. Batada, V. Gonzalez, L. Cassetta, C. K. Glass, S. J. Jenkins, J. W. Pollard
This study shows that mammary cancer in mice increases circulating and splenic monocytes without altering their ratios or half-lives, but changes their transcriptome, particularly in the bone marrow and blood, with differences from human breast cancer.
bioRxiv · Dec 24, 2021Cancer Biology