Z. Ouyang

KARS mediates intra-translational deposition of N6-acetyl-L-lysine in nascent proteins to contribute the acetylome in cells

The paper identifies KARS as mediating intra-translational deposition of N6-acetyl-L-lysine in nascent proteins, contributing to the acetylome in mice.

Generating Functional Cells Through Enhanced Interspecies Chimerism with Human Pluripotent Stem Cells

This study demonstrates that MYCN and BCL2 enhance interspecies chimerism with human pluripotent stem cells, enabling the generation of functional human blood progenitor cells in chimeric embryos.

Systemic influences of mammary cancer on monocytes in mice

This study shows that mammary cancer in mice increases circulating and splenic monocytes without altering their ratios or half-lives, but changes their transcriptome, particularly in the bone marrow and blood, with differences from human breast cancer.

The possible fidelity-speed-proofreading cost trade-offs in DNA replication due to the exonuclease proofreading

This paper re-examines fidelity-speed and fidelity-proofreading cost trade-offs in DNA replication under the exonuclease-proofreading mechanism using a first-passage method.

Sharpened and mechanically durable carbon fiber electrode arrays for neural interfacing

This paper develops durable carbon fiber electrode arrays for precise neural recording in rat and feline tissues, demonstrating their effectiveness in capturing neural signals from various structures.

Kinetic assays of DNA polymerase fidelity: a new theoretical perspective beyond Michaelis-Menten kinetics

This paper examines the theoretical basis of two DNA polymerase fidelity assays and shows they only accurately quantify proofreading efficiency under specific kinetic parameter constraints.

Closed-loop sacral neuromodulation for bladder function using dorsal root ganglia sensory feedback in an acute feline model

This study develops a closed-loop sacral neuromodulation system using DRG sensory feedback in felines, showing increased bladder capacity and reduced stimulation time.

Bladder pressure encoding by near-independent fibre subpopulations - implications for decoding

This paper analyzes how bladder pressure is encoded by sensory fibers in cats using information theory, showing redundancy and independence among neuron types that improve decoding robustness.

Anesthetic agents affect urodynamic parameters and anesthetic depth at doses necessary to facilitate preclinical testing in felines

This study evaluates how different anesthetic agents affect urodynamic and anesthetic parameters in cats during cystometrograms, guiding anesthetic selection for preclinical research.