Author

P. Matthys

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Assay:ChIP-seq· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. Antoranz· 1 shared A. Bassez· 1 shared A. de Visscher· 1 shared B. B. Manshian· 1 shared B. Vandekerckhove· 1 shared C. D. Rose· 1 shared C. Maksoudian· 1 shared C. Wouters· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCancer Biology

A. Antoranz

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

NK cells contribute to resistance to anti-PD1 therapy in immune-excluded melanomas

E. Landeloos, J. Pozniak, N. Roda, A. de Visscher, A. Antoranz, Y. van Herck, G. Bervoets, F. M. Bosisio, V. Boecxstaens, A. Bassez, D. Lambrechts, P. Matthys, O. Bechter, J.-C. Marine

The paper identifies NK cells as contributors to resistance to anti-PD1 therapy in immune-excluded melanomas using single-cell RNA sequencing and spatial proteomics.

bioRxiv · Dec 14, 2023 · PreprintCancer Biology

Multinucleation resets human macrophages for specialized functions at the expense of mononuclear phagocyte identity

K. Ahmadzadeh, M. Pereira, M. Vanoppen, E. Bernaerts, J.-H. Ko, T. Mitera, C. Maksoudian, B. B. Manshian, S. Soenen, C. D. Rose, P. Matthys, C. Wouters, J. Behmoaras

This study shows that multinucleation in human macrophages reduces mononuclear phagocyte identity and enables specialized functions in multinucleated giant cells.

bioRxiv · Aug 22, 2022Cell Biology

The transcription factor RUNX2 drives the generation of human NK cells and promotes tissue residency

S. Wahlen, F. Matthijssens, W. Van Loocke, S. Taveirne, L. Kiekens, E. Persyn, E. van Ammel, Z. De Vos, S. De Munter, P. Matthys, F. Van Nieuwerburgh, T. Taghon, B. Vandekerckhove, P. Van Vlierberghe, G. Leclercq

This study shows that RUNX2 promotes human NK cell generation and tissue residency through IL-2Rβ induction, with implications for cancer therapy.

bioRxiv · May 2, 2022Immunology